Phelps overjoyed to announce new baby John Lloyd Cruz a dashing guest at Vhong Navarro’s wedding Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles02:25PH women’s volleyball team motivated to deliver in front of hometown crowd01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City LATEST STORIES AFP official booed out of forum Typhoon Kammuri accelerates, gains strength en route to PH “It feels good, because last year was really tough for us and only winning one game it was hard so getting our second win, we’ve already our record and it feels good,” said Padda. “It shows that there’s been growth in the program and our team is not a pushover from last year.”Although the Lady Maroons managed to go hit-for-hit with the Lady Falcons in the second and third sets, the same can’t be said for the opening set when Adamson looked flawless.Adamson tallied eight service aces in the first set alone, and that mark was two more than UP scored in spikes.“That first set really hurt UP and our passing was really good,” said Padda as her team finished with 17 aces. “I’m surprised we got 17 aces, our team’s growing. And if we had to define us, I won’t define us as a strong serving team, we’re a strong defensive team.”Adamson outgunned UP, 40-26, in terms of spikes and was ahead 53-39 in excellent digs.ADVERTISEMENT Globe Business launches leading cloud-enabled and hardware-agnostic conferencing platform in PH NEXT BLOCK ASIA 2.0 introduces GURUS AWARDS to recognize and reward industry influencers Read Next Mylene Paat led Adamson with 15 points, eight coming off aces, while Galanza added 14.Mary Joy Dacoron and Chiara Permentilla also finished in double figures with 11 and 10 points, respectively.Carlos led UP with 12 points while Isa Molde added seven. Adamson wasted no time and handed University of the Philippines its second straight loss, 25-9, 27-25, 25-20, victory in the UAAP Season 80 women’s volleyball tournament Wednesday at Filoil Flying V Centre.ADVERTISEMENT Slow and steady hope for near-extinct Bangladesh tortoises MOST READ Brace for potentially devastating typhoon approaching PH – NDRRMC 2 ‘newbie’ drug pushers fall in Lucena sting The Lady Falcons soared to their second straight win for a 2-1 card, already eclipsing their one-win total from Season 79, while the Lady Maroons slipped to their second straight loss and a 1-2 record.With the Lady Falcons leading two sets to none and 23-18 in the third, Diana Carlos managed to score two straight points to cut the margin to three, 23-20, and give UP a semblance of fight.FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSLillard, Anthony lead Blazers over ThunderSPORTSMalditas save PH from shutoutCarlos’ back-to-back hits prompted Adamson head coach Air Padda to call time, and Jema Galanza calmed her mentor down with a pinpoint kill that went through UP’s defense and put the Lady Falcons at the 24-20 match point.UP’s Marian Buitre then gave Adamson the win when she failed to get the ball over from her side of the floor. Don’t miss out on the latest news and information. View comments
Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ Sports Related Videospowered by AdSparcRead Next Lacson: SEA Games fund put in foundation like ‘Napoles case’ Diaz said she wouldn’t be pleased with herself if she can’t take the gold medal in the AIMAG in Turkmenistan, where other Filipino athletes are also competing, from September 17 to 27.Simply put, it’s championship or bust for the 26-year-old weightlifter.“I have to set my mind that the only acceptable thing for me to bring home is the gold medal,” said Diaz. “I must be determined because I can’t be contented with what I am right now.”ADVERTISEMENT Hotel says PH coach apologized for ‘kikiam for breakfast’ claim Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games Don’t miss out on the latest news and information. Rio Olympians Kirstie Alora (left) and Hidilyn Diaz during a roundtable discussion at College of St. Benilde. Photo by Bong LozadaOlympian Hidilyn Diaz hasn’t competed in a major weightlifting tournament since her silver medal finish in the Rio Summer Games, and she heads to the Asian Indoor and Martial Arts Games knowing the pressure has built up.Most of the pressure, though, is coming from within.ADVERTISEMENT Robredo should’ve resigned as drug czar after lack of trust issue – Panelo MOST READ LATEST STORIES Celebrity chef Gary Rhodes dies at 59 with wife by his side NATO’s aging eye in the sky to get a last overhaul View comments Lyceum routs St. Benilde to stretch unbeaten run to 11 Trump signs bills in support of Hong Kong protesters “I’m not pressured by anyone except myself,” said Diaz in Filipino Thursday during a small luncheon with the media at College of St. Benilde, where she studies Business Management. “I always think to myself ‘do I still have it in me?’ because I was relaxed for four months.”Diaz became the poster girl of Philippine sports in 2016 when she ended the country’s 20-year medal drought winning the silver medal in the women’s -53 kilogram event.FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingHer triumph in Rio was her moment in the sun but after reaching the peak doubts have started to creep in.“The comeback is the hardest part, after so many tears I don’t know if I can ever return to that form,” said Diaz who lifted a total of 200 kg. in Rio. “I think this is why other medalists or champions quit after winning because it’s hard to sustain the strength and the discipline after all the accolades.” Celebrity chef Gary Rhodes dies at 59 with wife by his side
APTN National NewsAn Ontario Algonquin organization says it is pushing ahead with ratification votes for its agreement-in-principle for what it hopes will lead to a “modern-day treaty” that is facing opposition from Quebec Algonquin First NationsThe Algonquins of Ontario announced Wednesday the ratification votes would be held between Feb. 29 and March 7.The group is made up of 10 Algonquin communities, but only one, Pikwakanagan, is a First Nation with reserve lands. The nine other communities were given legitimacy by Queen’s Park and Ottawa within the framework of the proposed modern-day treaty talks.The Algonquins of Ontario (AOO) face stiff opposition to completing the proposed modern-day treaty from three Algonquin First Nations in Quebec.The First Nations, Wolf Lake, Eagle Village and Timiskaming alleged the AOO claim threatens to extinguish their rights and title to about 855,271 acres of their claimed territory in Ontario.The three First Nations are contemplating legal action to stop the AOO’s process. The communities also allege that some of the members who have signed up as part of the AOO are not real Indigenous people.Wolf Lake Chief Harry St. Denis has called the AOO a “policy fiction” that lacks the legitimacy of a real Algonquin nation.The agreement-in-principle proses to transfer $300 million in capital funding and 117,500 acres of Ontario Crown lands into the hands of AOO. The $300 million will likely not be distributed in lump sums among the signatories.A final agreement may still be years away from completion.Negotiations around the AOO’s claim began in earnest in about 2004 when the 10 Algonquin communities in Ontario signed a protocol to pursue the claim together.“The choice is now in the hands of Algonquin voters,” said Pikwakanagan First Nation Chief Kirby Whiteduck in a statement.In addition to Pikwakanagan, the AOO is comprised of the Antoine, Kijicho Manito Madaouskarini, Bonnechere, Greater Golden Lake, Mattawa-North Bay, Ottawa, Shabot Obaadjiwan, Snimikobi and Whitney communities.The AOO, Queen’s Park and Ottawa initialed the agreement-in-principle on June 12, email@example.com@APTNNews
http://news.rice.edu/wp-content/uploads/2016/01/02-01_PROTEIN-1-web.jpgRice University researchers observed nanoparticle aggregation induced by low concentrations of unfolded serum albumin proteins. They believe the proteins unfold upon binding to gold nanoparticles and prevent other proteins from joining them to form a protective casing around the particle. (Credit: Rice University) AddThis ShareEditor’s note: Links to images for download appear at the end of this release.David Ruth713firstname.lastname@example.orgMike Williams713email@example.comToo-few proteins prompt nanoparticles to clumpRice scientists: Blood serum proteins must find balance with therapeutic nanoparticles HOUSTON – (Jan. 28, 2016) – Blood serum proteins have been observed combining one-to-one with gold nanoparticles and prompting them to aggregate, scientists at Rice University reported.This is unexpected, according to Rice researchers Stephan Link and Christy Landes, who have led studies of the proteins most responsible for keeping solids in blood separated. In low concentrations, they said, the proteins irreversibly attach, unfold and then bring nanoparticles together.This is counter to the purpose of albumin proteins, the most abundant in the blood stream, they said.The paper, published this month in the American Chemical Society journal ACS Nano, has implications for diseases caused by aggregation, like Alzheimer’s, and for nanoparticle toxicity issues, the researchers said. Gold nanoparticles are increasingly being used as therapeutic agents.Several years ago the Rice team found that higher concentrations of bovine serum albumin (BSA), a near-match for its human counterpart, could keep naturally hydrophobic gold nanoparticles from clumping. In new experiments, some using technology that has only become available in recent years, BSA proteins in low concentrations were observed to unfold in the presence of gold nanoparticles.“We think the protein is attaching first and unfolding, and that prevents other proteins from coming in,” Link said. “But it also facilitates the aggregation.”“This is the most common protein in blood serum,” Landes said. “Its job is to surround and make a nice hard shell around anything in solution that would otherwise be insoluble and stabilize the complicated mixture of cells, proteins and hormones in blood.“What’s important is the protein’s ability to successfully coat otherwise hydrophobic steroid hormones, nanoparticles, viruses, anything,” she said. “But in order for it to make that coating, it needs to stay nicely folded.”By unfolding in the presence of gold nanoparticles, they said, the protein does two things: It spreads out on the particle, leaving no room for other proteins to attach, and exposes its usually hidden hydrophobic core, which encourages aggregation with other protein-nanoparticle sets.“This is an issue whether people use nanoparticles for therapeutic purposes or just come into contact with nanoparticles in products or the environment,” Landes said. “If serum albumin can do its job, everything’s fine. But we can’t help but notice that protein unfolding, protein aggregation and fibril formation are at the root of all sorts of diseases.”While their previous research showed albumin proteins in high concentrations keep nanoparticles soluble, “there are biological situations where the concentration of serum albumin protein could be low enough to cause problems,” Landes said.They also noted that two other blood-borne proteins, fibrinogen and globulin, cause gold nanoparticles to aggregate regardless of their concentrations. “They unfold no matter what the concentration, meaning that the BSA or human serum albumin are really designed to make this coating and keep everything from running out of control,” Link said.“We’re saying people really need to pay attention to the ratio between the protein – in this case, BSA – and nanoparticles, because different things can happen.”Co-lead authors of the paper are Rice alumni Sergio Dominguez-Medina, now a postdoctoral researcher at the French Atomic Energy and Alternatives Energy Commission in Grenoble, France; and Lydia Kisley, now a postdoctoral research associate at the Beckman Institute and the School of Chemical Sciences at the University of Illinois, Urbana-Champaign. Co-authors are Rice graduate students Lawrence Tauzin, Anneli Hoggard, Bo Shuang, Sishan Chen, Lin-Yung Wang and Paul Derry; postdoctoral researchers Swarnapali Indrasekara and Anton Liopo; and Eugene Zubarev, an associate professor of chemistry and of materials science and nanoengineering.Link and Landes are both associate professors of chemistry and of electrical and computer engineering.The National Science Foundation, the Welch Foundation and the National Institutes of Health funded the research.-30-Read the abstract at http://pubs.acs.org/doi/abs/10.1021/acsnano.5b06439This news release can be found online at http://news.rice.edu/2016/01/28/too-few-proteins-prompt-nanoparticles-to-clump/Follow Rice News and Media Relations via Twitter @RiceUNewsRelated Materials:Landes Research Group: http://www.lrg.rice.eduLink Research Group: http://slink.rice.eduWiess School of Natural Sciences: http://naturalsciences.rice.eduImages for download: http://news.rice.edu/wp-content/uploads/2016/01/02-01_PROTEIN-2-web.jpgThis is a super-resolution map of identified individual bovine serum albumin molecules, as marked by the colored outlines. The gold nanowire, in gray and thousands of nanometers long, shows the relative size of the proteins, which occupy areas much larger than expected based on the size of their unfolded geometry. The researchers said this supports the finding that there’s only space for one protein on the smaller nanoparticles studied. (Credit: Rice University)Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is home to the Baker Institute for Public Policy. With 3,910 undergraduates and 2,809 graduate students, Rice’s undergraduate student-to-faculty ratio is 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for best quality of life and for lots of race/class interaction by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger’s Personal Finance. To read “What they’re saying about Rice,” go to http://tinyurl.com/AboutRiceUniversity.