Nov 11, 2004 (CIDRAP News) – The outbreak of H5N1 avian influenza in Asia gives the world its first opportunity to prepare a vaccine in advance for a potential pandemic strain of flu, the World Health Organization (WHO) said today as it convened a meeting of vaccine companies and health officials to consider the challenge.Representatives of vaccine manufacturers and government officials from the manufacturers’ countries are meeting at WHO headquarters in Geneva, Switzerland, to discuss how to develop vaccines for pandemic flu.”The current outbreak of H5N1 is a stark warning that conditions are highly favourable for the emergence of a pandemic virus,” the WHO said in a statement on its Web site. “For the first time in history, there is a window of opportunity to consider using a pandemic vaccine in humans at a time when a virus with significant pandemic potential is circulating in large parts of Asia.”The H5N1 strain of avian flu has infected at least 44 people in Asia this year and has killed 32. The virus has not been known to spread from person to person, but experts fear that it could acquire this ability through mutation, potentially leading to a pandemic.The WHO noted that vaccines have never been available during past pandemics, including the last two, in 1957 and 1968, when annual vaccination programs for ordinary flu were fully established. Past pandemic strains were not discovered until they began spreading internationally, the agency said. The viruses spread worldwide in 6 to 8 months, far too short a time to develop and distribute a vaccine.A few companies have begun to develop vaccines for potential pandemic viruses, the WHO said. “However, production capacity for a pandemic vaccine will be vastly inadequate unless other companies engage in vaccine seed development and preparation of batches for clinical testing,” the agency said.The statement said vaccine makers face two major challenges: finding the optimal formulation for a pandemic vaccine through clinical trials, and registering their vaccine with their national drug licensing agency.”Such registration, done with a ‘template’ influenza subtype which will eventually be replaced by the strain actually causing the epidemic, is a condition which every manufacturer must fulfill to produce pandemic vaccine, regardless of when the next pandemic occurs and which strain causes it,” the WHO said.In the United States, Aventis Pasteur Inc. and Chiron Corp. each won a government contract last May to produce 8,000 to 10,000 doses of an H5N1 vaccine based on virus isolated from a Vietnamese patient. The National Institute of Allergy and Infectious Diseases said it would use the vaccines in clinical trials.In September, the Department of Health and Human Services (HHS) awarded a contract to Aventis Pasteur to make 2 million doses of its H5N1 vaccine for about $13 million. HHS officials then said clinical trials would start late this year or early next year.See also:WHO statement about Geneva meetinghttp://www.who.int/csr/disease/influenza/meeting2004_11_08/en/Sep 21, 2004, CIDRAP News story “HHS awards contract for H5N1 avian flu vaccine”May 28, 2004, CIDRAP News story, “NIAID seeks vaccines for H5N1 avian flu”
A tennis star has shown interest in a luxury beachfront home at 44-48 North Point Ave, Kingscliff.A LUXURY Kingscliff property has proved to be a hit with a tennis star who is in negotiations for the mansion that features a pool and tennis court.The resort-style property spans three beachfront blocks and has an eye-watering $6.995 million price tag.It has attracted plenty of interest since it was served up to the market in September.MORE NEWS: Construction king creates ultimate smart homeMORE NEWS: Second deal sealed for developer’s mansion Video Player is loading.Play VideoPlayNext playlist itemMuteCurrent Time 0:00/Duration 1:05Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -1:05 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedQuality Levels720p720pHD540p540p360p360p270p270pAutoA, selectedAudio Tracken (Main), selectedFullscreenThis is a modal window.Beginning of dialog window. 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This modal can be closed by pressing the Escape key or activating the close button.PlayMuteCurrent Time 0:00/Duration 0:00Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:00 Playback Rate1xFullscreenInside Kyle Sandilands $3 million country retreat01:05One of the potential buyers is said to be a high-profile female athlete who will make the most of the property’s full-sized, floodlit tennis court.The tennis player is looking to purchase the property as a home base.Not a bad spot for a hit of tennis.LJ Hooker Kingscliff agent Nick Witheriff, who is marketing the home alongside Carol Witheriff, could not reveal any further details on the prospective buyer.He expected a deal to be sealed within the next few weeks.“It’s unique because it is the only property available with a tennis court on the beachfront between Byron Bay and the Gold Coast,” Mr Witheriff said.“It’s also the only property that has just under 2000sq m of land over three separate lots.“With land prices now, the listing price is equivalent to land value so it’s a great opportunity for someone to buy well below replacement value.”More from news02:37International architect Desmond Brooks selling luxury beach villa9 hours ago02:37Gold Coast property: Sovereign Islands mega mansion hits market with $16m price tag1 day agoThe property has a $6.995 million price tag.A deal is set to be sealed within weeks.The five-bedroom house at 44-48 North Point Ave was designed by award-winning architect Paul Uhlmann and features beach access, an 18m resort-style saltwater pool and a parents’ retreat known as the ‘round house’.The interiors match the coastal surrounds with whitewashed oak floorboards, polished concrete flooring, custom stonework, large glass windows and doors and tropical gardens.Mr Witheriff likened the location to the Glitter Strip’s Millionaires’ Row.“This street is the jewel in the Tweed Coast crown — it’s the Hastings St of Noosa and the Hedges Ave of the Gold Coast,” he said.Video Player is loading.Play VideoPlayNext playlist itemMuteCurrent Time 0:00/Duration 1:01Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -1:01 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedQuality Levels720p720pHD540p540p360p360p270p270pAutoA, selectedAudio Tracken (Main), selectedFullscreenThis is a modal window.Beginning of dialog window. 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Press Association The 35-year-old will equal former Wallaby half-back Gregan’s Test appearance mark of 139, eight British and Irish Lions bows included. Boss Schmidt will field an unchanged starting XV against England from the side that demolished Wales 26-3, with O’Driscoll having shrugged off a midweek bug. Hailing O’Driscoll’s sheer stubborn will as central to his longevity, Schmidt said he would not bet against the talismanic midfielder guiding Ireland to the Triple Crown this weekend. “To be honest I didn’t play Test rugby so I wouldn’t be the best to judge, because I would think one Test would be phenomenal,” said Schmidt. “Where I grew up in a black jersey it would have been phenomenal, so how you manage to amass 130 of them, I’m not quite sure how you do it. “You have to be incredibly resilient, incredibly talented, a phenomenal professional, and there’s your summary: that’s Brian O’Driscoll. “I think he’s a very tough character, and the person he is allows him to be the player he’s been, and hopefully the player he will be on Saturday at four o’clock.” Should Schmidt’s men claim the Triple Crown on Saturday, O’Driscoll will seize his ninth career victory over England, breaking another Ireland record in the process. Former Ireland and Lions centre Mike Gibson’s eight wins over England is under threat then, with Schmidt admitting sometimes he bows to the greater experiences of the wily sages in his squad. O’Driscoll will retire at the end of the campaign with precious few unfulfilled aims in a startling career. Schmidt said he never turns down the chance to tap into the decade-plus Test ups and downs of the former captain, and current skipper Paul O’Connell to boot. “Thankfully I’ve got a lot of players who’ve drawn on a lot of experiences at Twickenham itself in the Test arena,” said Schmidt, conscious he remains an international coaching rookie. “We have very much a player-driven environment, they set the standard, I find them incredibly responsive when we’re looking at strategy and what we need to deliver technically and tactically. “But when it comes to directing and controlling the group it doesn’t need to be about what experiences I’ve had, or what I need to bring to the table. “It’s very much their experiences, and there is a good core of experienced players there, so they can lead that and give the younger players the confidence that they’ve been here before, they know what it takes and they’re ready to roll their sleeves up and live with that.” Leinster’s uncapped loose-forward Jordi Murphy is one of two changes to the bench to face England, with Ulster’s Iain Henderson replacing Dan Tuohy, who broke an arm in that Wales victory. Joe Schmidt admits he has no idea how Brian O’Driscoll has dredged up the staying power to equal George Gregan’s all-time Test appearance record. Ireland’s Kiwi head coach would have considered winning one All Blacks cap “phenomenal”, finding himself at a loss for how best to laud legendary centre O’Driscoll. O’Driscoll will add another impressive accolade to his bulging bag of record-breaking feats when Ireland take on England at Twickenham in the RBS 6 Nations on Saturday.
For all the Latest Sports News News, Other Sports News, Download News Nation Android and iOS Mobile Apps. New Delhi: Dipa Karmakar gave India fans plenty to cheer as she secured the bronze medal in the vault event of the Artistic Gymnastics World Cup event in Cottbus, Germany. Karmakar scored 14.316 to secure the bronze in the tournament, which is also a part of the eight-event qualifying system for the 2020 Tokyo Olympics. However, in the balance beam event, the Tripura athlete did not finish well. The Cottbus meet is part of an eight-event qualifying system for the 2020 Olympics, under which the gymnasts will make the cut based on the their top three scores. Speaking on Karmakar’s achievement, Gymnastics Federation of India vice-president Riyaz Ahmed Bhati said the Olympics qualification goal has come nearer.Read More |Hockey World Cup 2018: India seek repeat of 1975 glory“Karmakar has done well in the first tournament. She will be travelling to two more events out of Australia, Doha and Baku. But this event was the toughest,” Bhati said.Read More |Hero I-League wins silver at SPIA awardsThe 25-year-old has been plagued by a knee injury which she sustained in the Asian Artistic Gymnastics in Bangkok, Thailand. Karmakar underwent corrective surgery on her anterior cruciate ligament in April and was unable to participate throughout the season. Karmakar missed out on the 2018 Commonwealth Games. Although she had regained fitness, her coach Bisweshwar Nandi said her lengthy rehabilitation process resulted in her restricted training. Nandi said she was not yet ready fitness wise for the tournament.However, Karmakar created history in July 2018 as she won the gold medal in the FIG Artistic Gymnastics World Challenge Cup at Mersin, Turkey. Karmakar became the first Indian gymnast to win the gold medal in a world event. In the same competition, she reached the finals of the balance beam event where she finished a credible fourth.Karmakar was in confident mood heading into the 2018 Asian Games in Jakarta but in one of the practice sessions ahead of women’s qualification for team and apparatus finals, she hurt her right knee and she was forced to pull out of the final.